Work

Byproducts in the O-Phenyltetrazolylation of (±)-2,4-Dihydroxy-N-formylmorphinan-6-one. Alkylation at C-5

Year: 1982

Type: article

Abstract: 0-Alkylation of (+)-2.4-dihydroxy-N-f~mylmor~hioan-6-(4)with 5-chloro-1-phenyl-U-tetrazole in DXF in the presence of potassium carbonate afforded substantial amounts of the C-5 alkylated ketones 6 and? in addition to the desired ketone?.The structures of>, L a n d L w e r e supported by chemical correlation and on the basis of spectral data.

Source: Heterocycles

DOI: 10.3987/r-1982-11-2109

Authors: Arnold Brossi, Fu-Lian Hsu, Kenner C. Rice

Institutions: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases

Language: English

Topic: Alkaloids: synthesis and pharmacology

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: diamond

OpenAlex ID: W1997284130

FWCI:

Cites: 1

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Related to: 10