Work

(+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest

Year: 1996

Type: article

Source: Chemistry & Biology

DOI: 10.1016/s1074-5521(96)90108-8

Authors: Deborah T. Hung, Jie Chen, Stuart L. Schreiber

Institutions: Howard Hughes Medical Institute, Harvard University

Language: English

Topic: Microtubule and mitosis dynamics

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Institute of General Medical Sciences

Awards: Medical Scientist Training Program, G3653178687

OpenAlex ID: W1997607602

FWCI: 2.061

Cites: 22

Cited by: 139

Related to: 10