Work

Cover Picture: Single‐Particle Tracking and Modulation of Cell Entry Pathways of a Tetrahedral DNA Nanostructure in Live Cells (Angew. Chem. Int. Ed. 30/2014)

Year: 2014

Type: article

Abstract: Tetrahedral DNA nanostructures can be readily taken up by cells. In their Communication on page 7745 ff., C. Fan, Q. Huang, and co-workers investigate the endocytotic internalization into mammalian cells and subsequent transport of these self-assembled DNA nanostructures by single-particle tracking. These results constitute the next step toward the development of novel drug-delivery systems based on nucleic acids.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.201405099

Authors: Le Liang, Jiang Li, Qian Li, Qing Huang, Jiye Shi, Hao Yan, Chunhai Fan

Institutions: Chinese Academy of Sciences, Shanghai Institute of Applied Physics, Shanghai Synchrotron Radiation Facility, UCB Pharma (United Kingdom), Arizona State University

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W1998212343

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