Work

Interactions between acidic proteins and crystals: stereochemical requirements in biomineralization.

Year: 1985

Type: article

Abstract: Acidic matrix macromolecules are intimately involved in biological crystal growth. In vitro experiments, in which crystals of calcium dicarboxylate salts were grown in the presence of aspartic acid-rich proteins, revealed a stereochemical property common to all the interacting faces. Calcite crystals are nucleated on stereochemically analogous faces when proteins are adsorbed onto a rigid substrate. The importance of this property in biomineralization is discussed.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.82.12.4110

Authors: L Addadi, S Weiner

Institution: Weizmann Institute of Science

Language: English

Topic: Calcium Carbonate Crystallization and Inhibition

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W1998351418

FWCI: 12.7

Cites: 15

Cited by: 1,090

Related to: 10