Work

Possible correlation between blood glucose concentration and the reduced scattering coefficient of tissues in the near infrared

Year: 1994

Type: article

Abstract: Tissue glucose levels affect the refractive index of the extracellular fluid. The difference in refractive index between the extracellular fluid and the cellular components plays a role in determining the reduced scattering coefficient (micro(s)') of tissue. Hence a physical correlation may exist between the reduced scattering coefficient and glucose concentration. We have designed and constructed a frequency-domain near-infrared tissue spectrometer capable of measuring the reduced scattering coefficient of tissue with enough precision to detect changes in glucose levels in the physiological and pathological range.

Source: Optics Letters

DOI: 10.1364/ol.19.002062

Authors: John S. Maier, Scott A. Walker, Sergio Fantini, Maria Angela Franceschini, Enrico Gratton

Institution: University of Illinois Urbana-Champaign

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Center for Research Resources