Work

Spinal Cord Electrophysiology

Year: 2010

Type: article

Abstract: The neonatal mouse spinal cord is a model for studying the development of neural circuitries and locomotor movement. We demonstrate the spinal cord dissection and preparation of recording bath artificial cerebrospinal fluid used for locomotor studies. Once dissected, the spinal cord ventral nerve roots can be attached to a recording electrode to record the electrophysiologic signals of the central pattern generating circuitry within the lumbar cord.

Source: Journal of Visualized Experiments

DOI: 10.3791/1660

Authors: Allyn Meyer, Benjamin W. Gallarda, Samuel Pfaff, William Alaynick

Institutions: Salk Institute for Biological Studies, Howard Hughes Medical Institute, University of California San Diego

Language: English

Topic: Neuroscience and Neuropharmacology Research

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: bronze

Funders: Howard Hughes Medical Institute, Christopher and Dana Reeve Foundation, National Institute of Neurological Disorders and Stroke

Award: G557768473