Work

Il10 Deficiency Rebalances Innate Immunity to Mitigate Alzheimer-Like Pathology

Year: 2015

Type: article

Source: Neuron

DOI: 10.1016/j.neuron.2014.12.068

Authors: Marie-Victoire Guillot-Sestier, Kevin R. Doty, David Gate, Javier Rodriguez, Brian P. Leung, Kavon Rezai-Zadeh, Terrence Town

Institutions: University of Southern California, Pennington Biomedical Research Center, Louisiana State University

Language: English

Topic: Neuroinflammation and Neurodegeneration Mechanisms

Subfield: Neurology

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Institute on Aging, National Institute of Neurological Disorders and Stroke

Awards: G3652601006, Peripheral TGF-beta Pathway Inhibitor Therapy in Alzheimer's Rats, Targeting Abeta phagocytosis by blocking IRAK-M innate immunity in Alzheimer mice, Blocking TGF-Beta immune signaling as a therapeutic target for Alzheimer's diseas

OpenAlex ID: W1999516517

FWCI: 21.46

Cites: 79

Cited by: 372

Related to: 10