Upregulation of P53 Protein in Rat Heart Subjected to a Transient Occlusion of the Coronary Artery Followed by Reperfusion.
Year: 2000
Type: article
Abstract: The accumulation of p53 protein in cardiomyocyte nuclei was immunohistochemically demonstrated by the pronounced staining of p53 antibody in 4 h-reperfused ventricular tissue after a 45-min coronary occlusion. The occurrence of apoptosis in the reperfused ventricular tissue was evidenced by positive TUNEL staining and DNA laddering on agarose gels.
Authors: Zhonglin Xie, Tomiyasu Koyama, Kazuhiro Abe, Yukiko Fujii, Hirofumi Sawa, Kazuo Nagashima
Institution: Hokkaido University
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W1999716591