Work

Solubility of the Sesquiterpene Alcohol Patchoulol in Supercritical Carbon Dioxide

Year: 2006

Type: article

Abstract: The solubility of the sesquiterpene alcohol patchoulol in supercritical carbon dioxide was measured at P ranging from 10.0 MPa to 25.0 MPa and T of 40.0 and 50.0 °C using a simple microsampling type apparatus with a 100.5 µL sample loop to remove aliquots for off-line analysis. The system was first validated using vanillin with off-line spectrophotometric analysis, then utilized for patchoulol measurements with off-line GC-MS analysis. The measured solubility of patchoulol in supercritical CO(2) ranged from mole fractions of 0.43 × 10(-3) at 10.0 MPa and 50.0 °C to 9.45 × 10(-3) at 25.0 MPa and 40.0 °C.

Source: Journal of Chemical & Engineering Data

DOI: 10.1021/je060358w

Author: Brooks M. Hybertson

Institutions: University of Colorado Anschutz, University of Colorado Denver

Language: English

Topic: Phase Equilibria and Thermodynamics

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funders: National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of Allergy and Infectious Diseases

Awards: PROINFLAMMATORY ROLE OF URIC ACID IN LUNG DISEASE: NOVEL MODELS AND CLINICAL VALI, Respirable ciprofloxacin aerosol for inhaled anthrax, Lung cancer chemoprevention and tocopheryl succinate