Work

Participation of the serotonin2 receptor in the iminodipropionitrile-induced dyskinetic syndrome

Year: 1988

Type: article

Abstract: The effects of the specific serotonin2 antagonist ketanserin on the persistent lateral head shakes, vertical neck dyskinesia, and the random circling behaviors induced by iminodipropionitrile were evaluated. Ketanserin inhibited all these aspects of the behavioral syndrome at all doses tested. These results add further evidence for the involvement of the serotonin system in some of the components of the iminodipropionitrile-induced dyskinetic syndrome.

Source: Experimental Neurology

DOI: 10.1016/0014-4886(88)90175-6

Author: Jean Lud Cadet

Institution: Columbia University

Language: English

Topic: Parkinson's Disease Mechanisms and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,110