Work

Rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species

Year: 2014

Type: article

Abstract: Covering: 2006 to 2013. Investigations on the chemistry and biology of rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species during the period 2006-2013 are reviewed. Included are new phytochemical studies of naturally occurring rocaglamide derivatives, an update on synthetic methods for cyclopenta[b]benzofurans, and a description of the recent biological evaluation and mechanism-of-action studies on compounds of this type.

Source: Natural Product Reports

DOI: 10.1039/c4np00006d

Authors: Li Pan, John L. Woodard, David M. Lucas, James R. Fuchs, A. Douglas Kinghorn

Institution: The Ohio State University

Language: English

Topic: Bioactive Natural Diterpenoids Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Cancer Institute