Work

Enzymatic activity and filament assembly of Acanthamoeba myosin II are regulated by adjacent domains at the end of the tail

Year: 1988

Type: article

Abstract: Polyclonal antibodies raised against a synthetic peptide consisting of the last 19 amino acids at the end of the coiled-coil region of the heavy chains inhibited the actin-activated Mg2+-ATPase activity of myosin II and its ability to form filaments. Antibodies against a synthetic peptide corresponding to the 21 adjacent amino acids at the beginning of the non-helical tailpiece, which include the three regulatory phosphorylatable serines, had no effect on either activity.

Source: FEBS Letters

DOI: 10.1016/0014-5793(88)80132-7

Authors: Mark A.L. Atkinson, Ettore Appella, M.Angela Corigliano-Murphy, Edward D. Korn

Institutions: National Institutes of Health, National Heart, Lung, and Blood Institute, National Cancer Institute

Language: English

Topic: Cardiomyopathy and Myosin Studies

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

Open Access status: bronze

OpenAlex ID: W2001015124

FWCI: 2.141

Cites: 26

Cited by: 10

Related to: 10