Work

In vivo measurement of the average refractive index of the human crystalline lens using optical coherence tomography

Year: 2013

Type: article

Abstract: We present a method for measuring the average group refractive index of the human crystalline lens in vivo using an optical coherence tomography (OCT) system which, allows full-length biometry of the eye. A series of OCT images of the eye including the anterior segment and retina were recorded during accommodation. Optical lengths of the anterior chamber, lens, and vitreous were measured dynamically along the central axis on the OCT images. The group refractive index of the crystalline lens along the central axis was determined using linear regression analysis of the intraocular optical length measurements. Measurements were acquired on three subjects of age 21, 24, and 35 years. The average group refractive index for the three subjects was, respectively, n=1.41, 1.43, and 1.39 at 835 nm.

Source: Optics Letters

DOI: 10.1364/ol.38.000085

Authors: Carolina de Freitas, Marco Ruggeri, Fabrice Manns, Arthur Ho, Jean-Marie Parel

Institution: University of Miami

Language: English

Topic: Optical Coherence Tomography Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Research to Prevent Blindness, Henri and Flore Lesieur Foundation, National Eye Institute