Work

Stabilizing a Flexible Interdomain Hinge Region Harboring the SMB Binding Site Drives uPAR into Its Closed Conformation

Year: 2015

Type: article

Source: Journal of Molecular Biology

DOI: 10.1016/j.jmb.2015.01.022

Authors: Baoyu Zhao, Sonu Gandhi, Cai Yuan, Zhipu Luo, Rui Li, Henrik Gårdsvoll, Valentina de Lorenzi, Nicolai Sidenius, Mingdong Huang, Michael Ploug

Institutions: Chinese Academy of Sciences, Fujian Institute of Research on the Structure of Matter, State Key Laboratory of Structural Chemistry, IFOM, University of Copenhagen, Rigshospitalet

Language: English

Topic: Protease and Inhibitor Mechanisms

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: Danmarks Grundforskningsfond, National Natural Science Foundation of China, Chinese Academy of Sciences, Associazione Italiana per la Ricerca sul Cancro, CAS-SAFEA International Partnership Program for Creative Research Teams

Awards: G1303360118, G2200402724, G2604983931, G2770292651, 纤溶酶原激活物抑制因子及其新型抑制剂的结构研究, G5055216714, G6314093954, G7458479793, G7846320785, G8608786510

OpenAlex ID: W2002072990

FWCI: 0.441

Cites: 63

Cited by: 29

Related to: 10