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An altered zinc-binding site confers resistance to a covalent inactivator of New Delhi metallo-beta-lactamase-1 (NDM-1) discovered by high-throughput screening

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Year: 2013
Type: article
Source: Bioorganic & Medicinal Chemistry
DOI: 10.1016/j.bmc.2013.03.031
Authors: Pei W. Thomas, Timothy Spicer, Michael Cammarata, Jennifer S. Brodbelt, Peter Hodder, Walter Fast
Institutions: The University of Texas at Austin, Scripps Research Institute
Language: English

Topic: Antibiotic Resistance in Bacteria
Subfield: Molecular Medicine
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Welch Foundation, National Institute of Mental Health, National Institute of General Medical Sciences
Awards: The Comprehensive Center for Chemical Probe Discovery and Optimization at Scripps, UV Photodissociation for Acidic and Basic Proteome Characterization, G6296143508
OpenAlex ID: W2002722687
FWCI: 1.381
Cites: 34
Cited by: 44
Related to: 10
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