Prospective motion correction for magnetic resonance spectroscopy using single camera retro‐grate reflector optical tracking
Year: 2011
Type: article
Abstract: PURPOSE: To introduce and evaluate a method of prospective motion correction for localized proton magnetic resonance spectroscopy (1H-MRS) using a single-camera optical tracking system. MATERIALS AND METHODS: Five healthy participants were scanned at 3T using a point-resolved spectroscopic sequence (PRESS) with a motion-tracking module and phase navigator. Head motion in six degrees was tracked with a Retro-Grate Reflector (RGR) tracking system and target via a mirror mounted inside the bore. Participants performed a series of three predetermined motion patterns during scanning. RESULTS: Left-right rotation (Rz) (average 12°) resulted in an increase in the total choline to total creatine ratio (Cho/Cr) of +14.6 ± 1.5% (P = 0.0009) for scans without correction, but no change for scans with correction (+1.1 ± 1.5%; P = 0.76). Spectra with uncorrected Z-translations showed large lipid peaks (skull) with changes in Cho/Cr of -13.2 ± 1.6% (P = 0.02, no motion correction) and -2.2 ± 2.4% (P = 0.51) with correction enabled. There were no significant changes in the ratios of N-acetylaspartate, glutamate+glutamine, or myo-inositol to creatine compared to baseline scans for all experiments. CONCLUSION: Prospective motion correction for 1H-MRS, using single-camera RGR tracking, can reduce spectral artifacts and quantitation errors in Cho/Cr ratios due to head motion and promises improved spectral quality and reproducibility.
DOI: 10.1002/jmri.22467
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funders: National Institutes of Health, Centers for Disease Control and Prevention, U.S. Public Health Service, National Institute on Drug Abuse, National Institute of Neurological Disorders and Stroke, National Center for Research Resources, National Institute on Minority Health and Health Disparities
Awards: RGR-based motion tracking for real-time adaptive MR imaging and spectroscopy, G1244017850, Imaging Studies in Neurotoxicity and Neurodevelopment, G3035002106, Bioscience Research Infrastructure Development for Grant Enhancement and Success, G37190882, MR Techniques for Drug Abuse and HIV Brain Research, G7165415505, G8488744920, G9000321635
OpenAlex ID: W2002724932