Work

Palladium‐Catalyzed Carboetherification and Carboamination Reactions of γ‐Hydroxy‐ and γ‐Aminoalkenes for the Synthesis of Tetrahydrofurans and Pyrrolidines

Year: 2006

Type: article

Abstract: Substituted tetrahydrofuran and pyrrolidine moieties are displayed in a wide range of interesting biologically active molecules. The Pd-catalyzed carboetherification or carboamination of γ-hydroxy- and γ-aminoalkenes is a powerful tool for the construction of these heterocycles, as it is convergent and can allow access to a variety of analogs from a single γ-hydroxy- or γ-aminoalkene starting material. This microreview describes the current state of this field.

Source: European Journal of Organic Chemistry

DOI: 10.1002/ejoc.200600767

Author: John P. Wolfe

Institution: University of Michigan

Language: English

Topic: Catalytic Cross-Coupling Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze