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P5-S6.19 Prevalence and incidence of sexually transmitted infections among female sex workers in two cities in India: implications for STI control strategies

Year: 2011

Type: article

Abstract: Background India is a large country with marked heterogeneity in prevalence of sexually transmitted infections (STIs) which has implications for STI control strategies. The study objective was to measure the prevalence and incidence of common bacterial STIs in a cohort of female sex workers (FSWs) in known high STI prevalence cities in response to a package of standardised interventions under Avahan, the India AIDS Initiative of the Bill & Melinda Gates Foundation. Methods FSWs attending clinics were followed up periodically over 6–9 months. At every visit, vaginal swabs were tested forNeisseria gonorrhoeae(GC) andChlamydia trachomatis(CT) by Gen-Probe APTIMA Combo II. During the baseline and final visits, vaginal swabs were tested forTrichomonas vaginalis(TV) by PCR and blood was tested for syphilis using Rapid Plasma Reagin (RPR) with confirmatoryTreponema pallidumHaemagglutination Assay (TPHA). All participants received presumptive treatment for gonorrhoea and chlamydia at the baseline visit and syndromic STI management at all subsequent visits. Results A total of 417 FSWs were recruited, 360 returned for at least one follow-up visit, and 282 completed the final visit. The total follow-up period was 109.4 person years (median 0.18 years, maximum 1.07 years). Self-reported consistent condom use with commercial and regular partners was 70% and 17%, respectively. A substantial proportion of cervical and trichomonal infections were asymptomatic (see Abstract P5-S6.19 table 1). The incidence of GC/CT and TV was 1.0 and 2.0 per person year respectively. Three new cases of latent syphilis were detected at the final visit. Abstract P5-S6.19 Table 1 Prevalence of STIs and asymptomatic infections (n=282) Pathogen Baseline visit 1st follow-up Final visit Cervical infections (GC and/or CT) 27.7% (asymptomatic 35.9%) 16.7% (asymptomatic 60.5%) 21.3% (asymptomatic 76.7%) TV 29.9% (asymptomatic 27.2%) 46.6% (asymptomatic 82.2%) Latent syphilis (RPR titre >1:8) 6.8% 2.5% Conclusions The incidence of GC, CT and TV and the considerable burden of asymptomatic infections indicate the need for periodic presumptive treatment at high STI prevalence sites in India. The current regime of bi-annual syphilis screening is justified. Consistent condom use and partner treatment, particularly for regular partners, need to be re-emphasised.

Source: Sexually Transmitted Infections

DOI: 10.1136/sextrans-2011-050108.575