Work

Magnetomotive optical coherence elastography using magnetic particles to induce mechanical waves

Year: 2014

Type: article

Abstract: Magnetic particles are versatile imaging agents that have found wide spread applicability in diagnostic, therapeutic, and rheology applications. In this study, we demonstrate that mechanical waves generated by a localized inclusion of magnetic nanoparticles can be used for assessment of the tissue viscoelastic properties using magnetomotive optical coherence elastography. We show these capabilities in tissue mimicking elastic and viscoelastic phantoms and in biological tissues by measuring the shear wave speed under magnetomotive excitation. Furthermore, we demonstrate the extraction of the complex shear modulus by measuring the shear wave speed at different frequencies and fitting to a Kelvin-Voigt model.

Source: Biomedical Optics Express

DOI: 10.1364/boe.5.002349

Authors: Adeel Ahmad, Jongsik Kim, Nahil A. Sobh, Nathan D. Shemonski, Stephen A. Boppart

Institution: University of Illinois Urbana-Champaign

Language: English

Topic: Ultrasound Imaging and Elastography

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,913