Work

Cellular Functionality on Nanotubes of Ti-30Ta Alloy

Year: 2014

Type: article

Abstract: Recent studies have identified strong correlations between anodized metals and the production of highly biomimetic nanoscale topographies. These surfaces provide an interface of enhanced biocompatibility that exhibits a high degree of oxidation and surface energy. In this study, Human dermal fibroblasts (HDF, neonatal) were utilized to evaluate the biocompatibility of Ti-30Ta nanotubes after 1 day of culture. The anodization process was performed in an electrolyte solution containing HF (48%) and H2SO4 (98%) in the volumetric ratios 1:9 with the addition of 5% dimethyl sulfoxide (DMSO) at 35V for 40 min. Cellular analysis identified improved fibroblast functionality on the nanotube surface, showing increased elongation, and extracellular matrix production on the Ti-30Ta nanotubes. The results presented identify improved cellular interaction on Ti-30Ta nanotubes as compared to the control substrates. Thus, the formation of the nanotube on Ti30Ta alloy may have potential application as interface for implantable devices.

Source: Materials science forum

DOI: 10.4028/www.scientific.net/msf.805.61

Authors: Patricia Capellato, Barbara S. Smith, Ketul C. Popat, Ana P.R. Alves Claro

Institutions: Universidade Estadual Paulista (Unesp), Colorado State University

Language: English

Topic: Anodic Oxide Films and Nanostructures

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2003488479

FWCI: 0.151

Cites: 11

Cited by: 11

Related to: 10