Work

Extended 6-Month Follow-Up of A Randomized Clinical Trial to Assess the Efficacy and Safety of Real-Time Continuous Glucose Monitoring in the Management of Type 1 Diabetes in Young Children Aged 4 to <10 Years

Year: 2013

Type: article

Abstract: In a 6-month randomized trial of continuous glucose monitoring (CGM) in children 4–9 years of age with type 1 diabetes (1), the DirecNet Study Group reported no difference in change in A1C between the CGM and usual care groups, although parents expressed high satisfaction with use of CGM. In a 6-month posttrial phase, the CGM group continued to use CGM and the control group was started on CGM. This observation provides a summary of the findings for both groups during this posttrial phase. Sixty-four of the 69 children in the CGM group who completed the trial participated in the extension phase; all 64 completed the 12-month visit. Baseline A1C was 7.9 ± 0.8 and 7.8 ± 0.8% at the beginning of the extension phase and 7.9 ± 0.8% at 12 months. During the extension phase, A1C decreased ≥0.5% in 14% and increased ≥0.5% in 25%. Sensor use dropped from a median of 92 h/week at 6 months to …

Source: Diabetes Care

DOI: 10.2337/dc12-2021

Authors: Michael Tansey, Stuart Weinzimer, Roy Beck, Katrina Ruedy, Peiyao Cheng, William Tamborlane, Craig Kollman, Nelly Mauras, Larry Fox, Julie Coffey, Neil H. White

Institutions: University of Iowa, Yale University, Jaeb Center for Health Research, Nemours Children’s Clinic, Nemours Children's Clinic, Washington University in St. Louis

Language: English

Topic: Diabetes Management and Research

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: National Institutes of Health, National Center for Research Resources, National Center for Advancing Translational Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: Coordinating Center for Studies of Glucose Sensors in T*, Prevention of Nocturnal Hypoglycemia: Effect on Neurologic Outcome in Toddlers, Stanford Center for Clinical and Translational Education and Research (SCCTER)UL1, Hypoglycemia in Children and Adolescents with T1DM: Mechanisms and Prevention, University of Iowa Clinical and Translational Science Program (UL1), Cooperative Multicenter Diabetes Research Network for Hypoglycemia Prevention, Prevention of Hypoglycemia and Associated Complications in Type 1 Diabetes, Washington University Institute of Clinical and Translational Sciences, Washington University Institute of Clinical and Translational Sciences (UL1), Yale University Clinical and Translational Science Award Program, Diabetes Research in Children Network (DirecNet), Yale Study of Closed-Loop Automated Glucose Control for Hypoglycemia Prevention

OpenAlex ID: W2003823689

FWCI: 2.097

Cites: 2

Cited by: 14

Related to: 10