Year: 2008
Type: review
Abstract: NKG2D is a potent activating receptor on NK cells and a co-stimulatory receptor on CD8+ T cells. Through its ability to recognize a panel of ligands inducible by stress or infection, it plays an important role in the control of viral infections. The viruses have evolved robust mechanisms to counteract NKG2D-dependent immune response. The functions of these viral inhibitors are well characterized during the early days post-infection but less so during the chronic viral infection.
Source: European Journal of Immunology
Authors: Stipan Jonjić, Bojan Polić, Astrid Krmpotić
Institution: University of Rijeka
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
Funder: Howard Hughes Medical Institute
OpenAlex ID: W2004205395