Work

Modulating water-exchange rates of lanthanide(iii)-containing polyaminopolycarboxylate-type complexes using polyethylene glycol

Year: 2013

Type: article

Abstract: We have synthesized a series of Ln(III)-containing polyethylene glycol conjugates and studied the structural and electronic properties of these complexes. These studies demonstrate that polyethylene glycol can be used to fine-tune water-exchange rates of Ln(III)-containing polyaminopolycarboxylate-type complexes; this control is desirable in developing Ln(III)-containing contrast agents for magnetic resonance imaging.

Source: Dalton Transactions

DOI: 10.1039/c3dt50885d

Authors: Buddhima N. Siriwardena-Mahanama, Matthew J. Allen

Institution: Wayne State University

Language: English

Topic: Lanthanide and Transition Metal Complexes

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of Biomedical Imaging and Bioengineering

Award: Increasing the Utility of Contrast Agents for MRI