Work

Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride

Year: 2012

Type: article

Source: The Journal of Steroid Biochemistry and Molecular Biology

DOI: 10.1016/j.jsbmb.2011.12.012

Authors: Michael C. Byrns, Rebekka Mindnich, Ling Duan, Trevor M. Penning

Institution: University of Pennsylvania

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Prostate Cancer Foundation, National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Environmental Health Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: Research and Training in Reproductive Biology, G3179421147, Human aldo-keto reductases and nuclear receptor action, G6014662730, Center of Excellence in Environmental Toxicology, Diabetes, Endocrine, and Metabolism

OpenAlex ID: W2004422115

FWCI: 2.784

Cites: 33

Cited by: 60

Related to: 10