Work

A benzothiazole-based sensor for pyrophosphate (PPi) and ATP: mechanistic insight for anion-induced ESIPT turn-on

Year: 2014

Type: article

Abstract: A benzothiazole derivative 2 bearing two 2,2′-dipicolylamine (DPA) groups was examined for its zinc-binding and subsequent anion sensing properties. The study revealed the anion sensing mechanism of polyphosphate anions via sequential binding to two zinc centers, on the basis of both 1H NMR and mass spectral evidence. The mechanistic insight would provide valuable information for the future design of new excited state intramolecular proton transfer (ESIPT) sensors. In addition, the zinc complex exhibited solvent-switchable selectivity, responding to pyrophosphate (PPi) in EtOH and adenosine 5′-triphosphate (ATP) in water.

Source: Journal of Materials Chemistry B

DOI: 10.1039/c4tb01109k

Authors: Junfeng Wang, Xiumin Liu, Yi Pang

Institution: University of Akron

Language: English

Topic: Molecular Sensors and Ion Detection

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: Ohio Department of Development, University of Akron, National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering

Award: Binuclear Complexes with Excited-State Proton Transfer for Pyrophosphate Sensor