Outcomes After Non-Myeloablative Allogeneic Hematopoietic Cell Transplantation with Total Lymphoid Irradiation and Anti-Thymocyte Globulin in Lymphoid Malignancies After Failed Autologous Transplantation
Year: 2013
Type: article
Abstract: Patients with lymphoid malignancies who relapse after autologous hematopoietic cell transplantation (HCT) have few curative treatment options. Allogeneic HCT using full dose conditioning can cure selected patients but high non-relapse mortality (NRM) limits its broad applicability. We developed reduced intensity conditioning for allogeneic HCT with total lymphoid irradiation and rabbit anti-thymocyte globulin (TLI-ATG) that was safe, well tolerated, protected against GVHD and allowed for retained graft-versus tumor reactions.
Institutions: Stanford Medicine, Stanford University
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2005328474