Work

CCR5, RANTES and SDF‐1 polymorphisms and mother‐to‐child HIV‐1 transmission

Year: 2010

Type: article

Study design: Observational Study

Abstract: Summary Among 288 HIV-1-infected, breastfeeding women who received zidovudine prophylaxis and were followed with their infants in Nairobi, we found no associations between maternal genetic polymorphisms in CCR5 (59029G/A, 59353T/C, 59356T/C, 59402G/A), RANTES (-403G/A) and SDF-1 (3'801G/A) and mother-to-child HIV-1 transmission; plasma, cervical and breastmilk viral loads; or breastmilk chemokine concentrations.

Source: International Journal of Immunogenetics

DOI: 10.1111/j.1744-313x.2010.00924.x

Authors: D. A. Katz, G. C. John‐Stewart, B. A. Richardson, M. Majiwa, J. M. Mabuka, B. Lohman‐Payne, C. Farquhar

Institutions: University of Washington, Fred Hutch Cancer Center, University of Nairobi

Language: English

Topic: HIV Research and Treatment

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Elizabeth Glaser Pediatric AIDS Foundation, National Institute of Allergy and Infectious Diseases, Fogarty International Center, National Institute of Dental and Craniofacial Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: CCR5 and CXCR4 Binding Chemokines and Oral HIV Infection, Pediatric HIV-1 in Africa: Pathogenesis and Management, G2312769785, G2935578525, AIDS International Training and Research Program, Protective Immune Responses in HIV-1 Exposed Infants, University of Washington/Fred Hutch Center for AIDS Research, Pediatric HIV reservoir determinants and consequences

OpenAlex ID: W2005331803

FWCI: 0.338

Cites: 35

Cited by: 7

Related to: 10