Year: 2003
Type: article
Abstract: The regulation of metabolic flux is essential for life, yet our understanding of it remains incomplete. The ability to determine the role of specific enzymes in regulating metabolic flux rapidly becomes a nearly overwhelming challenge due to the various interacting pathways, multiple enzyme isoforms, and many different substrates that are involved. This complexity is further compounded by the fact that the enzymes themselves are regulated by multiple mechanisms. Moreover, the amount of an enzyme in a particular cell may be modulated by a variety of transcriptional and post-transcriptional mechanisms.
Source: Journal of Biological Chemistry
Institution: Vanderbilt University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,430
OpenAlex ID: W2005398956