Year: 2010
Type: article
Abstract: The purpose of this paper is to evaluate the feasibility and clinical dosimetric benefit of an on-line, that is, with the patient in the treatment position, Adaptive Radiation Therapy (ART) system for prostate cancer treatment based on daily cone-beam CT imaging and fast volumetric reoptimization of treatment plans. A fast intensity-modulated radiotherapy (IMRT) plan reoptimization algorithm is implemented and evaluated with clinical cases. The quality of these adapted plans is compared to the corresponding new plans generated by an experienced planner using a commercial treatment planning system and also evaluated by an in-house developed tool estimating achievable dose-volume histograms (DVHs) based on a database of existing treatment plans. In addition, a clinical implementation scheme for ART is designed and evaluated using clinical cases for its dosimetric qualities and efficiency.
Source: Journal of Oncology
DOI: 10.1155/2010/407236
Authors: Taoran Li, Xiaofeng Zhu, Danthai Thongphiew, W. Robert Lee, Zeljko Vujaskovic, Qiuwen Wu, Fang-Fang Yin, Q. Jackie Wu
Institutions: Duke Medical Center, East Carolina University
Language: English
Subfield: Radiation
Field: Physics and Astronomy
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $2,550
Funder: Varian Medical Systems
OpenAlex ID: W2005612944