Work

Obsessive‐compulsive disorder is not a clinical manifestation of the DYT1 dystonia gene

Year: 2006

Type: article

Abstract: Prior studies suggest that obsessive-compulsive symptoms (OCS) and disorder (OCD) are co-morbid with dystonia. We tested if OCS/OCD is a clinical manifestation of the DYT1 dystonia mutation by interviewing members of families with an identified DYT1 mutation, and classifying by manifesting carriers (MC), non-manifesting carriers (NMC), and non-carriers (NC). We found that OCD/OCS are not increased in DYT1 mutation carriers compared with NC, nor is OCD associated with manifesting DYT1 dystonia.

Source: American Journal of Medical Genetics Part B Neuropsychiatric Genetics

DOI: 10.1002/ajmg.b.30431

Authors: Gary A. Heiman, Ruth Ottman, Rachel J. Saunders‐Pullman, Laurie J. Ozelius, Neil J. Risch, Susan B. Bressman

Institutions: Columbia University, New York State Psychiatric Institute, Albert Einstein College of Medicine, University of California, San Francisco

Language: English

Topic: Obsessive-Compulsive Spectrum Disorders

Subfield: Clinical Psychology

Field: Psychology

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Institute of Neurological Disorders and Stroke