Work

Recombining the structures of HIV integrase, RuvC and RNase H

Year: 1995

Type: article

Abstract: The recently reported crystal structures of two recombination enzymes, the catalytic domain of HIV integrase and Escherichia coli RuvC, an endonuclease, are surprisingly similar to that of ribonuclease H suggesting the possibility that they have a common enzymatic mechanism.

Source: Structure

DOI: 10.1016/s0969-2126(01)00142-3

Authors: Wei Yang, Thomas A Steitz

Institutions: Howard Hughes Medical Institute, Yale University

Language: English

Topic: Enzyme Structure and Function

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $9,350

Funders: National Institutes of Health, National Institute of General Medical Sciences