Work

Improving the in Vitro Prediction of in Vivo Central Nervous System Penetration: Integrating Permeability, P-glycoprotein Efflux, and Free Fractions in Blood and Brain

Year: 2006

Type: article

Source: Journal of Pharmacology and Experimental Therapeutics

DOI: 10.1124/jpet.105.092916

Authors: Scott G. Summerfield, Alexander J. Stevens, Leanne Cutler, Maria del Carmen Osuna, Beverley Hammond, Sac-Pham Tang, Ann Hersey, David J. Spalding, Phil Jeffrey

Institutions: GlaxoSmithKline (United Kingdom), GlaxoSmithKline Research & Development Limited (United Kingdom)

Language: English

Topic: Drug Transport and Resistance Mechanisms

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: American Society for Pharmacology and Experimental Therapeutics

OpenAlex ID: W2006669174

FWCI: 8.791

Cites: 20

Cited by: 181

Related to: 8