Work

Improving Monoclonal Antibody Selection and Engineering using Measurements of Colloidal Protein Interactions

Year: 2014

Type: article

Source: Journal of Pharmaceutical Sciences

DOI: 10.1002/jps.24130

Authors: Steven B. Geng, Jason K. Cheung, Chakravarthy Narasimhan, Mohammed Shameem, Peter M. Tessier

Institutions: Rensselaer Polytechnic Institute, Merck & Co., Inc., Rahway, NJ, USA (United States)

Language: English

Topic: Monoclonal and Polyclonal Antibodies Research

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funders: National Science Foundation, National Institutes of Health, National Institute of General Medical Sciences, Division of Chemical, Bioengineering, Environmental, and Transport Systems

Awards: Design of conformation-specific antibodies against unfolded and misfolded proteins, G2443809039, CAREER: Loop engineering of protein surfaces for tunable self-association and phase behavior, G9000021190

OpenAlex ID: W2006806491

FWCI: 5.301

Cites: 82

Cited by: 65

Related to: 10