Work

Is protection against shigellosis induced by natural infection with Plesiomonas shigelloides?

Year: 1994

Type: article

Abstract: Shigellosis due to Shigella sonnei is rare among people growing up and living in developing countries; however, infections due to S sonnei becomes more common than those due to S flexneri as societies develop economically. The relation between risk of S sonnei infection and economic development may be explained by the exposure of developing-country populations to Plesiomonas shigelloides. P shigelloides is often found in surface water, and one serotype (serotype 17) possesses a cell-wall lipopolysaccharide identical to that of S sonnei. Thus, exposure to P shigelloides by drinking contaminated water may immunise populations to S sonnei. As economic development occurs, water quality improves and populations become susceptible to S sonnei. Although drinking water has many advantages, immunisation against S sonnei may be one benefit of traditional water sources.

Source: The Lancet

DOI: 10.1016/s0140-6736(94)92531-3

Authors: D.A. Sack, Shamsul Hoque, M. Etheridge, A. Huq

Institution: Johns Hopkins University

Language: English

Topic: Escherichia coli research studies

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDGs: Good health and well-being, Clean water and sanitation

Open Access status: hybrid

Estimated APC paid: $7,890