Work

Methods for the inclusion of shallow marrow and adipose tissue in pathlength-based skeletal dosimetry

Year: 2011

Type: article

Abstract: Distributions of linear pathlength measurements have been utilized in skeletal dosimetry of internally emitted short-range particles for over 30 years. This work reviews the methods for coupling these distributions to range-energy data. A revised methodology is presented for handling the insertion of the additional dosimetric target region (shallow marrow) and medium (adipose tissue) into the dosimetry algorithm. The methodology is shown to reduce the volume fraction of shallow marrow in the trabecular skeleton over existing methodologies. Finally, theoretical low and high-energy checkpoints are derived for use in checking the absorbed fraction and specific absorbed fraction results for a variety of source and target combinations.

Source: Physics in Medicine and Biology

DOI: 10.1088/0031-9155/56/9/004

Authors: D W Jokisch, D A Rajon, P W Patton, W E Bolch

Institutions: Francis Marion University, University of Florida Health, University of Florida, University of Nevada, Las Vegas

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2007117203

FWCI: 0.922

Cites: 19

Cited by: 10

Related to: 10