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HIV protease (HIV PR) inhibitor structure‐activity‐selectivity, and active site molecular modeling of high affinity Leu [CH(OH)CH2]Val modified viral and nonviral substrate analogs

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Year: 1992
Type: article
Source: International journal of peptide & protein research
DOI: 10.1111/j.1399-3011.1992.tb00302.x
Authors: TOMI K. SAWYER, DOUGLAS J. STAPLES, LI LIU, ALFREDO G. TOMASSELLI, JOHN O. HUI, KATHY O'CONNELL, HEINRICH SCHOSTAREZ, JACKSON B. HESTER, JOSEPH MOON, W. JEFFREY HOWE, CLARCK W. SMITH, DIANNE L. DECAMP, CHARLES S. CRAIK, BEN M. DUNN, W. TODD LOWTHER, JESSICA HARRIS, ROGER A. POORMAN, ALEXANDER WLODAWER, MARIUSZ JASKOLSKI, ROBERT L. HEINRIKSON
Institutions: University of California, San Francisco, University of Florida, Frederick National Laboratory for Cancer Research
Language: English

Topic: HIV/AIDS drug development and treatment
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: MECHANISMS OF PEPSIN CATALYSIS AND INHIBITION, BASIC RESEARCH--CANCER INSTITUTE FREDERICK, G225764842, G2731579658
OpenAlex ID: W2007207724
FWCI: 2.748
Cites: 20
Cited by: 10
Related to: 10
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