Year: 2014
Type: article
Study design: Observational Study
Abstract: Rapid, accurate, and cost-effective methods to identify the cause of respiratory tract infections are needed to maximize clinical benefit. Outpatients with acute respiratory illness were tested for influenza using a singleplex reverse transcriptase polymerase chain reaction (SRT-PCR) method. A multiplex RT-PCR (MRT-PCR) method tested for influenza and 17 other viruses and was compared with SRT-PCR using chi-square tests. Among 935 patients, 335 (36%) tested positive for influenza A and influenza B using SRT-PCR. Using MRT-PCR, 320 (34.2%) tested positive for influenza A and influenza B. This study supports MRT-PCR as a comparable method for detecting influenza among patients seeking outpatient care for acute respiratory illnesses.
Source: Advances in Virology
DOI: 10.1155/2014/274679
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,000
Funders: U.S. Department of Health and Human Services, Pfizer, University of Pittsburgh, National Institutes of Health, Centers for Disease Control and Prevention, Sanofi Pasteur, National Institute on Aging, National Center for Research Resources, National Center for Advancing Translational Sciences
OpenAlex ID: W2007373310