Work

Quantifying the Performance of Protein‐Resisting Surfaces at Ultra‐Low Protein Coverages using Kinesin Motor Proteins as Probes

Year: 2007

Type: article

Abstract: The binding kinetics of fluorescently labeled microtubules to kinesin-coated surfaces permits the determination of the density of kinesin motor proteins adhered to the surface in the range of 0.1 – 30 μm–2. This extreme sensitivity, corresponding to protein coverages of 0.004 – 1 ng cm–2, enables the characterization of advanced non-fouling coatings, such as (EG)3OH-terminated SAMs and PEGMA with applications in biomedical engineering and bionanotechnology.

Source: Advanced Materials

DOI: 10.1002/adma.200701982

Authors: P. Katira, A. Agarwal, T. Fischer, H.‐Y. Chen, X. Jiang, J. Lahann, H. Hess

Institutions: University of Florida, University of Michigan

Language: English

Topic: Polymer Surface Interaction Studies

Subfield: Surfaces, Coatings and Films

Field: Materials Science

Domain: Physical Sciences

Open Access status: bronze

Funders: National Science Foundation, U.S. Department of Energy, Defense Advanced Research Projects Agency, Division of Materials Research, Basic Energy Sciences

Awards: CAREER: An Integrated Research and Education Plan for the Advancement of Surface Engineering via Thin Polymer Films, G6671297155, G6916253724, MRI: Acquisition of a X-ray Photoelectron Spectrometer for Multidisciplinary Materials Research at the University of Michigan

OpenAlex ID: W2007502298

FWCI: 3.564

Cites: 49

Cited by: 55

Related to: 10