Work

β-D-Arabinosyl 1-C-sulfonic acid

Year: 2012

Type: article

Abstract: A short synthetic route to β,D-arabinofuranosyl 1-C-sulfonic acid (7), a possible biomimetic for the arabinofuranosyl anomeric phosphate, is described. The furanosyl 1-C-sulfonate was prepared by buffered dimethyldioxirane oxidation of an S-acetyl-1-thio-β-arabinofuranose derivative. Deprotection under mild conditions allowed isolation of the free sulfonic acid without desulfonylation.

Source: Journal of Sulfur Chemistry

DOI: 10.1080/17415993.2012.706814

Authors: Walter S. Won, Spencer Knapp

Institution: Rutgers, The State University of New Jersey

Language: Hebrew

Topic: Carbohydrate Chemistry and Synthesis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of Allergy and Infectious Diseases

Award: Inhibition of Tubercular Mycothiol Pathways