Work

Glass‐Bead‐Based Parallel Detection of DNA Using Composite Raman Labels

Year: 2006

Type: article

Abstract: Gold nanoparticles are co-functionalized with multiple types of Raman-dye-labeled oligonucleotides (see picture) to prepare composite Raman labels for DNA targets that are used in a glass-microbead-based multiplexed DNA detection system in conjunction with surface-enhanced Raman scattering (SERS) spectroscopy. The narrow bands of the Raman spectra of the dye-labeled nanoparticles allow for greater degrees of multiplexing when compared to the broad absorption and emission bands of molecular fluorophores.

Source: Small

DOI: 10.1002/smll.200500322

Authors: Rongchao Jin, Y. Charles Cao, C. Shad Thaxton, Chad A. Mirkin

Institutions: Northwestern University, International Institute for Nanotechnology

Language: English

Topic: Gold and Silver Nanoparticles Synthesis and Applications

Subfield: Electronic, Optical and Magnetic Materials

Field: Materials Science

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W2007902064

FWCI: 4.587

Cites: 46

Cited by: 74

Related to: 10