Work

Asymmetric Counteranion‐Directed Catalytic Hosomi–Sakurai Reaction

Year: 2012

Type: article

Abstract: Counteranion control enables the enantioselective, organo Lewis acid catalyzed Hosomi-Sakurai reaction of (hetero)aromatic aldehydes and allylsilanes using an easily handled disulfonimide precatalyst (see scheme). The key to the success of this system is to turn the usually undesired silylium ion catalysis into the desired catalytic regime and pair the cation with an enantiopure disulfonimide anion, thereby applying the concept of asymmetric counteranion-directed catalysis.

Source: Chemistry - A European Journal

DOI: 10.1002/chem.201203623

Authors: Manuel Mahlau, Pilar García‐García, Benjamin List

Institutions: Max Planck Society, Max-Planck-Institut für Kohlenforschung

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: Max-Planck-Gesellschaft

OpenAlex ID: W2008224435

FWCI: 4.562

Cites: 94

Cited by: 83

Related to: 10