Work

Markers of Field Cancerization: Proposed Clinical Applications in Prostate Biopsies

Year: 2012

Type: article

Abstract: Field cancerization denotes the occurrence of genetic, epigenetic, and biochemical aberrations in structurally intact cells in histologically normal tissues adjacent to cancerous lesions. This paper tabulates markers of prostate field cancerization known to date and discusses their potential clinical value in the analysis of prostate biopsies, including diagnosis, monitoring progression during active surveillance, and assessing efficacy of presurgical neoadjuvant and focal therapeutic interventions.

Source: Prostate Cancer

DOI: 10.1155/2012/302894

Authors: Kristina A. Trujillo, Anna C. Jones, Jeffrey K. Griffith, Marco Bisoffi

Institutions: University of New Mexico Health Sciences Center, New Mexico Cancer Center, UNM Comprehensive Cancer Center

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,000