Work

Needle-based reflection refractometry of scattering samples using coherence-gated detection

Year: 2007

Type: article

Abstract: We present a novel method for in situ refractive index measurement of scattering samples using a needle device. The device employs a fiber-based reflectance refractometer and coherence-gated detection of the reflected optical signal that eliminates scattering-dependent backreflection contributions. Additionally, birefringence changes induced by fiber movement are neutralized by randomizing the source polarizations and averaging the measured Fresnel reflection coefficients over many incident polarization states. Experimental measurements of Intralipid scattering solutions are presented and compared with Monte Carlo simulations.

Source: Optics Express

DOI: 10.1364/oe.15.004787

Authors: Adam M. Zysk, Daniel L. Marks, Dianna Y. Liu, Stephen A. Boppart

Institutions: University of Illinois Urbana-Champaign, General Electric (United States), Carle Foundation Hospital

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $2,270

Funders: Carle Foundation Hospital, National Institutes of Health, Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana-Champaign