Work

Function of RIG-I-like Receptors in Antiviral Innate Immunity

Year: 2007

Type: review

Abstract: Various cells in the body are capable of sensing infectious viruses and initiating reactions collectively known as antiviral innate responses. These responses include the production of antiviral cytokines such as type I interferon (IFN)2 and subsequent synthesis of antiviral enzymes, which are responsible for the impairment of viral replication and promoting adaptive immune responses (1). In this minireview, we focus on a subset of molecules known as RIG-I-like receptors, which sense viral RNA molecules that trigger a danger signal.

Source: Journal of Biological Chemistry

DOI: 10.1074/jbc.r700007200

Authors: Mitsutoshi Yoneyama, Takashi Fujita

Institution: Kyoto University

Language: English

Topic: interferon and immune responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,430