Work

Probing the molecular mechanism of action of the HIV-1 reverse transcriptase inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) using pre-steady-state kinetics

Year: 2014

Type: article

Source: Antiviral Research

DOI: 10.1016/j.antiviral.2014.03.001

Authors: Yagmur Muftuoglu, Christal D. Sohl, Andrea C. Mislak, Hiroaki Mitsuya, Stefan G. Sarafianos, Karen S. Anderson

Institutions: Yale University, National Institutes of Health, National Cancer Institute, Kumamoto University, University of Missouri

Language: English

Topic: HIV/AIDS drug development and treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: G1767093982, Hepatitis C antivirals: Mechanism of action, combination efficacy and resistance, Mechanism and Inhibition of HIV Reverse Transcriptase, G5996103371, G7216027917, Novel antivirals targeting the RNase H activity of HIV reverse transcriptase, Ultrapotent Inhibitors of Wild-type and Multi-drug Resistant HIV, HIV Macromolecular Interactions and Impact on Viral Evolution of Drug Resistance, Kinetics of DNA polymerase gamma upon mutation and nucleoside analog exposure, G9000192372, G9000355206, Ultrapotent Inhibitors of Wild-type and Multi-drug Resistant HIV

OpenAlex ID: W2010120019

FWCI: 1.87

Cites: 26

Cited by: 20

Related to: 10