Work

Molecular Targeted α-Particle Therapy for Oncologic Applications

Year: 2014

Type: review

Abstract: OBJECTIVE: A significant challenge facing traditional cancer therapies is their propensity to significantly harm normal tissue. The recent clinical success of targeting therapies by attaching them to antibodies that are specific to tumor-restricted biomarkers marks a new era of cancer treatments. CONCLUSION: In this article, we highlight the recent developments in α-particle therapy that have enabled investigators to exploit this highly potent form of therapy by targeting tumor-restricted molecular biomarkers.

Source: American Journal of Roentgenology

DOI: 10.2214/ajr.14.12554

Authors: Thaddeus J. Wadas, Darpan N. Pandya, Kiran Kumar Solingapuram Sai, Akiva Mintz

Institutions: Atrium Health Wake Forest Baptist, Wake Forest University Health Sciences, Wake Forest University

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Cancer Institute