Work

A Photoresponsive Supramolecular G-Quadruplex

Year: 2013

Type: article

Abstract: Photoirradiation of a hexadecameric supramolecular G-quadruplex leads to a diastereoselective [2 + 2] cyclodimerization of half of its constituent subunits, which in turn shifts the equilibrium toward the formation of a precise heteromeric octamer.

Source: Organic Letters

DOI: 10.1021/ol400610x

Authors: José M. Rivera, Diana Silva-Brenes

Institutions: University of Puerto Rico at Río Piedras, University of Puerto Rico System

Language: English

Topic: DNA and Nucleic Acid Chemistry

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Awards: Small Molecule Self-Assembly in Aqueos Media, Support for University Biomedical Excellence at UPR-RP