Work

Plasma catecholamine metabolites and treatment response at neuroleptic steady state

Year: 1989

Type: article

Abstract: Using either haloperidol or perphenazine in a fixed-dose protocol, plasma free homovanillic acid (HVA) and methoxyhydroxyphenethylglycol (MHPG) were decreased in 37 nonorganic psychotic inpatients at neuroleptic steady state (7-9 days) in comparison with pretreatment values. The data indicate that the magnitude of the decline in HVA and MHPG was associated with treatment response and not with neuroleptic plasma levels.

Source: Biological Psychiatry

DOI: 10.1016/0006-3223(89)90245-x

Authors: Malcolm B. Bowers, Mary E. Swigar, Peter I. Jatlow, Frederick J. Huffman

Institution: Yale University

Language: English

Topic: Schizophrenia research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $5,489