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Simultaneous inhibition of glutathione- and thioredoxin-dependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress

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Year: 2011
Type: article
Source: Free Radical Biology and Medicine
DOI: 10.1016/j.freeradbiomed.2011.10.493
Authors: Peter M. Scarbrough, Kranti A. Mapuskar, David M. Mattson, David Gius, Walter H. Watson, Douglas R. Spitz
Institutions: University of Iowa, University of Iowa Holden Comprehensive Cancer Center, Roswell Park Comprehensive Cancer Center, National Institutes of Health, Vanderbilt University, National Cancer Institute, Center for Cancer Research, Vanderbilt-Ingram Cancer Center, University of Louisville
Language: English

Topic: Redox biology and oxidative stress
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute
Awards: G280538892, The Use of 2-Deoxyglucose in Head and Neck Cancer Therapy, G3301332164, Metabolic Oxidative Stress in Human Cancer Cells, G630064964, Training Program in Free Radical and Radiation Biology, Cancer Center Support Grant
OpenAlex ID: W2010728263
FWCI: 2.938
Cites: 37
Cited by: 82
Related to: 10
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