Work

Building the posterior lateral line system in zebrafish

Year: 2011

Type: review

Abstract: The posterior lateral line (pLL) in zebrafish has emerged as an excellent system to study how a sensory organ system develops. Here we review recent studies that illustrate how interactions between multiple signaling pathways coordinate cell fate,morphogenesis, and collective migration of cells in the posterior lateral line primordium. These studies also illustrate how the pLL system is contributing much more broadly to our understanding of mechanisms operating during the growth, regeneration, and self-organization of other organ systems during development and disease.

Source: Developmental Neurobiology

DOI: 10.1002/dneu.20962

Authors: Ajay B. Chitnis, Damian Dalle Nogare, Miho Matsuda

Institutions: National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Language: English

Topic: Zebrafish Biomedical Research Applications

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: Investigation of the role of Mind bomb in epithelial morphogenesis, Building the Posterior Lateral Line system In Zebrafish Embryos